Bone Marrow Transplant

Bone Marrow Transplant

Advanced treatment for blood disorders and hematologic cancers

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What is Bone Marrow Transplantation?

Bone marrow transplantation (BMT), also known as hematopoietic stem cell transplantation, is a medical procedure that replaces damaged or destroyed bone marrow with healthy bone marrow stem cells. This life-saving treatment is used for patients with various blood disorders, cancers, and immune system diseases.

The procedure involves collecting healthy stem cells from the patient (autologous) or a matched donor (allogeneic), then infusing them into the patient after intensive chemotherapy or radiation therapy to eliminate diseased cells.

Conditions Treated

Bone marrow transplantation can treat various serious conditions

Acute & Chronic Leukemia

Hodgkin & Non-Hodgkin Lymphoma

Multiple Myeloma

Aplastic Anemia

Immune Deficiency Disorders

Sickle Cell Disease

Types of Bone Marrow Transplant

Autologous Transplant

Uses the patient's own stem cells, collected before high-dose chemotherapy or radiation. Lower risk of complications and no need for donor matching, commonly used for lymphoma and multiple myeloma.

Allogeneic Transplant

Uses stem cells from a matched donor (sibling, unrelated donor, or cord blood). Provides graft-versus-disease effect but carries higher risk of complications. Essential for many leukemias and genetic disorders.

Transplant Process

A comprehensive journey from evaluation to recovery

1

Medical Evaluation & Donor Search

Comprehensive health assessment, disease staging, and HLA typing. For allogeneic transplants, donor search through registries or family members.

2

Conditioning Regimen

High-dose chemotherapy and/or radiation therapy to eliminate diseased cells and suppress the immune system to prevent rejection.

3

Stem Cell Collection

Harvesting stem cells from bone marrow, peripheral blood, or umbilical cord blood, depending on the transplant type.

4

Transplant Infusion

Stem cells are infused intravenously, similar to a blood transfusion. The cells travel to the bone marrow and begin producing new blood cells.

5

Engraftment & Recovery

Close monitoring during engraftment (typically 2-4 weeks), managing complications, and long-term follow-up care with immunosuppressive medications.

Factors Affecting Success

  • Disease type and stage at transplant—earlier stages generally have better outcomes
  • Donor match quality—closer HLA matching reduces complications in allogeneic transplants
  • Patient age and overall health—younger patients with fewer comorbidities typically recover better
  • Transplant center experience—high-volume centers demonstrate superior outcomes

Expert Bone Marrow Transplant Care

Our specialized hematology teams provide comprehensive bone marrow transplant services with state-of-the-art facilities and personalized care protocols.

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